Population: 500 participants for aim 1 (male and female, aged 18 years and older, PLWH), 990 participants for aim 2 (PLWH, who received TPT) Study Sites: Mbarara Regional Referral Hospital Immune Suppression Syndrome (ISS) Clinic, Mbarara, Uganda Mbarara City Council Clinic HIV clinics in Mbarara, Ibanda and Rubirizi districts Background: Tuberculosis (TB) is...
Tuberculosis is the leading cause of death among persons with HIV worldwide, and HIV-infected drinkers are at very high risk for Tuberculosis (TB) disease and mortality. Six months of isoniazid (INH) preventive therapy (IPT) reduces TB morbidity and mortality by 30-50% above the benefit of antiretroviral therapy (ART). However, INH...
Overview: Although digital adherence technologies (DATs) are promising patient-centered strategies for monitoring TB medication adherence, ethical opportunities and concerns associated with using DATs in monitoring TB medication adherence (e.g., autonomy, beneficence) have not been empirically examined. In response to NOT-OD-21-020: Administrative Supplement for Research and Capacity Building Efforts Related to...
Information coming soon
The DISCO study is a prospective observational cohort study at government-supported HIV clinics in rural South Africa and Uganda, which began in 2019. In the first phase of the study, we enrolled adults with HIV who were switched from first-line antiretroviral therapy (ART) containing non-nucleoside reverse transcriptase inhibitors (NNRTIs) to...
Background: Maternal mortality rate remains unacceptably high in Uganda. In-depth evidence about the barriers to access and utilization of maternal health services specifically among the rural illiterate pregnant women remains lacking. The potentials of mobile health technologies in addressing the maternal health challenges remain unclear. Aim: To...
Overview: This study develops My Mobile Wallet—a behavioral and economic intervention to support tuberculosis (TB) treatment adherence among 327 TB patients initiating treatment at Mbarara Regional Referral Hospital in Uganda. We will first determine the optimal design and develop the My Mobile Wallet intervention and assess its initial feasibility and...
Overview: Antenatal care (ANC) is a mainstay of preventing maternal and perinatal morbidity and mortality but utilization of these services in Uganda remains low. Consequently, maternal and perinatal mortality rates are among the highest in the world. Short message service (SMS) and other mobile health (mHealth) interventions have been proposed...
“Advancing HIV/AIDS research is a research administration training program at Mbarara University of Science and Technology(MUST) in collaboration with the University of Virginia” is funded under Grant Number: 1G11TW010948-01A1. The major objective of the study is to strengthen research administration through a Research Administration Training Program with the University of Virginia,...
